When sexually aroused, the body releases nitric oxide, which triggers the relaxation of blood vessels in the penis. This relaxation allows increased blood flow, leading to an erection. In cases of ED, the PDE5 enzyme breaks down cyclic guanosine monophosphate (cGMP), which interferes with the process. Tadalafil inhibits PDE5, promoting the accumulation of cGMP and facilitating the natural process of achieving an erection.
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