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Dextrans are naturally synthesized polysaccharides with good water solubility, low toxicity and varied molecular weights. These azide functionalized dextrans conjugates are reactive toward alkyne or dibenzylcyclooctyne (DBCO) groups via so called Click Chemistry, used as long-term tracers for live cells. These functional dextrans were purified by size chromatography to remove non-conjugated molecules and ensure adequate applications both in-vitro and in-vivo.

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